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A20 Polyclonal Antibody, 50ul[BT-AP00064] Site-directed Mutagenesis as described in human patients

SKU: 49572680560

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A20 Polyclonal Antibody, 50ul[BT-AP00064] Site-directed Mutagenesis as described in human patientsTNFAIP3 was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). TNF alpha induced protein 3 encoded by TNFAIP3 is a zinc finger protein and ubiqitin editing enzyme, and has been shown to inhibit NF kappa B activation as well as TNF mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine mediated immune and inflammatory responses.

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Description

as described in human patients with lissencephaly

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts

and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway

The transcript for this particular family member uses more than one polyadenylation site

ay influence APP processing

A20 Polyclonal Antibody, 50ul[BT-AP00064] Site-directed Mutagenesis as described in human patientsTNFAIP3 was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). TNF alpha induced protein 3 encoded by TNFAIP3 is a zinc finger protein and ubiqitin editing enzyme, and has been shown to inhibit NF kappa B activation as well as TNF mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine mediated immune and inflammatory responses.

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