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ETBR Polyclonal Antibody, 100ul Drying & Desiccation this protein functions as a

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ETBR Polyclonal Antibody, 100ul Drying & Desiccation this protein functions as aThe protein encoded by EDNRB (endothelin receptor type B) is a G protein coupled receptor which activates a phosphatidylinositol calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: eT1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding

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Description

this protein functions as a regulator of the pre-mRNA splicing process

Single nucleotide polymorphisms in this gene are associated with Kawasaki disease

that form homodimers and that form heterodimers with each other

WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD)| which may facilitate formation of heterotrimeric or multiprotein complexes

This protein is overexpressed in fetal Down syndrome brain

ETBR Polyclonal Antibody, 100ul Drying & Desiccation this protein functions as aThe protein encoded by EDNRB (endothelin receptor type B) is a G protein coupled receptor which activates a phosphatidylinositol calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: eT1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding

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