LIS1 Rabbit Polyclonal Antibody, 100ul Purification The encoded protein has been

The encoded protein has been shown to control the cellular level of FBXL7| a protein that induces mitotic arrest| by targeting it for polyubiquitylation and proteasomal degradation

MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al

Beta subunits are important regulators of alpha subunits

Mutations in this gene are associated with ataxia telangiectasia| an autosomal recessive disorder

serves several important biosynthetic pathways

LIS1 Rabbit Polyclonal Antibody, 100ul Purification The encoded protein has beenThis locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller Dieker lissencephaly syndrome. This gene encodes the non catalytic alpha subunit of the intracellular Ib isoform of platelet activating factor acteylhydrolase a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN 2 position of platelet activating factor (identified as 1 O alkyl 2 acetyl sn