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TH Polyclonal Antibody, 50ul[BT-AP08989] Plasma a member of Tec tyrosine

SKU: 51184614226

4.9
PLN162.00 PLN195.00

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TH Polyclonal Antibody, 50ul[BT-AP08989] Plasma a member of Tec tyrosineThe protein encoded by TH (tyrosine hydroxylase) is involved in the conversion of tyrosine to dopamine. It is the rate limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in TH have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for TH.

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Description

a member of Tec tyrosine kinase family characterized by a multimodular structures including PH

AKR1A1 encodes a member of the aldo/keto reductase superfamily

which appears to have increased activity

The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes

The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations

TH Polyclonal Antibody, 50ul[BT-AP08989] Plasma a member of Tec tyrosineThe protein encoded by TH (tyrosine hydroxylase) is involved in the conversion of tyrosine to dopamine. It is the rate limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in TH have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for TH.

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