CCG8 Polyclonal Antibody, 50ul Glassware Mutations at this locus have

Mutations at this locus have been associated with autosomal dominant spastic paraplegia-12

Interacts with subunit of G(i) alpha proteins and regulates the activation of G(i) alpha proteins

This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family

This gene encodes a core centrosomal protein required for centriole-centriole cohesion during interphase of the cell cycle

Some transcripts are predicted to be capable of translation reinitiation at a downstream AUG

CCG8 Polyclonal Antibody, 50ul Glassware Mutations at this locus haveThe protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight member protein subfamily of the PMP 22 EMP MP20 family and is located in a cluster with two family members, a type II TARP and a calcium channel gamma subunit. The mRNA for this gene is believed to initiate translation from a non