HMG-1 (Acetyl Lys12) Polyclonal Antibody, 50ul Dry Bath The huntingtin locus is large|

The huntingtin locus is large| spanning 180 kb and consisting of 67 exons

hematopoetic tumors such as B-cell lymphomas

The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits

The encoded protein undergoes a change in conformational state and activity

20-lyase deficiency

HMG-1 (Acetyl Lys12) Polyclonal Antibody, 50ul Dry Bath The huntingtin locus is large|HMGB1 encodes a protein that belongs to the High Mobility Group box superfamily. The encoded non histone, nuclear DNA binding protein regulates transcription, and is involved in organization of DNA. High mobility group box 1 plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of HMGB1 have been identified. Alternative splicing results in multiple transcript variants