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Neurofibromin Polyclonal Antibody, 50ul Glassware Sets cause factor IX deficiency

SKU: 53335948718

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PLN162.00 PLN188.00

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Neurofibromin Polyclonal Antibody, 50ul Glassware Sets cause factor IX deficiencyNF1 product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA >Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.

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Description

cause factor IX deficiency

The expression of this gene is up-regulated by interferon gamma in Th1 cells

non-integrin family

The inner- and outer-arm dyneins

The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity

Neurofibromin Polyclonal Antibody, 50ul Glassware Sets cause factor IX deficiencyNF1 product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA >Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.

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