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FRS3 Polyclonal Antibody, 100ul Bottles This gene is regulated by

SKU: 53705650508

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PLN123.75 PLN172.75

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FRS3 Polyclonal Antibody, 100ul Bottles This gene is regulated byFRS3 encodes a substrate for the fibroblast growth factor receptor. Fibroblast growth factor receptor substrate 3 is found in the peripheral plasma membrane and links fibroblast growth factor receptor stimulation to activators of Ras. Fibroblast growth factor receptor substrate 3 down regulates extracellular regulated kinase 2 through direct binding.

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Description

This gene is regulated by the transcription factors ZNF444/EZF-2 and SP1

Studies in rat indicate that the protein is translated from a non-AUG translation initiation site

It is located within a homozygously deleted region of a metastatic prostate cancer

and also ovarian hyperstimulation syndrome

May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death

FRS3 Polyclonal Antibody, 100ul Bottles This gene is regulated byFRS3 encodes a substrate for the fibroblast growth factor receptor. Fibroblast growth factor receptor substrate 3 is found in the peripheral plasma membrane and links fibroblast growth factor receptor stimulation to activators of Ras. Fibroblast growth factor receptor substrate 3 down regulates extracellular regulated kinase 2 through direct binding.

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