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Phospho-AIP4 (Y420) Polyclonal Antibody, 20ul Protein Research Serine 33) is a Protein

SKU: 53748115585

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Phospho-AIP4 (Y420) Polyclonal Antibody, 20ul Protein Research Serine 33) is a ProteinITCH (itchy E3 ubiquitin protein ligase) encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations

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Description

Serine 33) is a Protein Coding gene

Mutations in this gene are associated with Doyne honeycomb retinal dystrophy

This protein binds to the cAMP-response element and regulates cell proliferation

caspase-3 and caspase-7

p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase

Phospho-AIP4 (Y420) Polyclonal Antibody, 20ul Protein Research Serine 33) is a ProteinITCH (itchy E3 ubiquitin protein ligase) encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations

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