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TM165 Rabbit Polyclonal Antibody, 20ul Recombinant Protein CMTM8 (CKLF like MARVEL transmembrane

SKU: 54212603588

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TM165 Rabbit Polyclonal Antibody, 20ul Recombinant Protein CMTM8 (CKLF like MARVEL transmembraneThis gene encodes a predicted transmembrane protein with a perinuclear Golgi like distribution in fibroblasts. Mutations in this gene are associated with the autosomal recessive disorder congenital disorder of glycosylation type IIk. Knockdown of this gene's expression causes decreased sialylation in HEK cells and suggests this gene plays a role in terminal Golgi glycosylation. Alternative splicing results in multiple transcript variants.

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Description

CMTM8 (CKLF like MARVEL transmembrane domain containing 8) belongs to the chemokine-like factor gene superfamily

In addition| this subunit| in combination with several other polymerase subunits| forms the DNA binding domain of the polymerase| a groove in which the DNA template is transcribed into RNA

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PPARs affect the expression of target genes involved in cell proliferation

Krueppel-like factor 11 encoded by KLF11 is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters

TM165 Rabbit Polyclonal Antibody, 20ul Recombinant Protein CMTM8 (CKLF like MARVEL transmembraneThis gene encodes a predicted transmembrane protein with a perinuclear Golgi like distribution in fibroblasts. Mutations in this gene are associated with the autosomal recessive disorder congenital disorder of glycosylation type IIk. Knockdown of this gene's expression causes decreased sialylation in HEK cells and suggests this gene plays a role in terminal Golgi glycosylation. Alternative splicing results in multiple transcript variants.

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