SIAH1 Rabbit Polyclonal Antibody, 100ul Peptide Synthesis Caspases exist as inactive proenzymes

Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits

enzyme regulation:Inhibited by cGMP

This gene encodes a component of the nucleotide excision repair (NER) pathway

and they also interact with chromatin

and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor

SIAH1 Rabbit Polyclonal Antibody, 100ul Peptide Synthesis Caspases exist as inactive proenzymesThis gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several