Human Macrophage Inflammatory Protein-3Α, MIP-3A ELISA Kit , 96T ADME 'Trans-signaling' in central nervous system

'Trans-signaling' in central nervous system also regulates energy and glucose homeostasis (By similarity)

May play a role in maintenance and/or transport of vesicles

These receptors are members of the G protein-coupled receptor superfamily

The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor

There are two transcripts identified for this gene

Human Macrophage Inflammatory Protein-3Α, MIP-3A ELISA Kit , 96T ADME 'Trans-signaling' in central nervous systemActs as a ligand for C C chemokine receptor CCR6. Signals through binding and activation of CCR6 and induces a strong chemotactic response and mobilization of intracellular calcium ions (PubMed: 11352563, PubMed: 11035086, PubMed: 20068036). The ligand receptor pair CCL20 CCR6 is responsible for the chemotaxis of dendritic cells (DC), effector memory T cells and B cells and plays an important role at skin and mucosal surfaces under homeostatic and