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SF3A3 Polyclonal Antibody, 50ul Bottle-Top Dispenser An important paralog of this

SKU: 56012627610

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SEK162.00 SEK200.00

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SF3A3 Polyclonal Antibody, 50ul Bottle-Top Dispenser An important paralog of thisThis gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre mRNA splicing. Subunit 3 interacts with subunit 1 through its amino terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20.

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Description

An important paralog of this gene is GPR45

Among its related pathways are Gene Expression and Cell Cycle

Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain

The rat protein stimulates the activity of some Rho GTPases in vitro

and belongs to the mitochondrial porin family

SF3A3 Polyclonal Antibody, 50ul Bottle-Top Dispenser An important paralog of thisThis gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre mRNA splicing. Subunit 3 interacts with subunit 1 through its amino terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20.

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