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PDX-1 Polyclonal Antibody, 100ul Sample Library Tubes functions as a calcium regulator

SKU: 56299282316

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PDX-1 Polyclonal Antibody, 100ul Sample Library Tubes functions as a calcium regulatorThe protein encoded by PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early onset insulin dependent

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Description

functions as a calcium regulator in the mitochondria of skeletal muscle

and the expression of this gene is a potential marker for cancer

Members of this family encode enzymes that catalyze the specific addition of sulfate groups to distinct hydroxyl and amino groups of carbohydrates

This dissociation from the centrosome is phosphorylation-dependent

Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS)

PDX-1 Polyclonal Antibody, 100ul Sample Library Tubes functions as a calcium regulatorThe protein encoded by PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early onset insulin dependent

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