Smad4 Polyclonal Antibody, 20ul Pathway and Network Analysis Kit includes choice of hydrogel

Kit includes choice of hydrogel with 12 x VitroPrime™® Cell Culture Inserts

Specific mutations in DYSF have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy

Type I interferon required for maintaining basal levels of IFN-regulated genes

interacting with other transcription factors through a tetrapeptide domain in its C-terminus

Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation

Smad4 Polyclonal Antibody, 20ul Pathway and Network Analysis Kit includes choice of hydrogelSMAD4 encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine threonine receptor kinases in response to TGF beta signaling. The product of SMAD4 forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8 bp