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Oct-3/4 Monoclonal Antibody, 50ul[BT-MCA0954] Drug Development and Evaluation Canalicular multispecific organic anion transporter

SKU: 57218137651

4.7
USD185.00 USD227.00

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Oct-3/4 Monoclonal Antibody, 50ul[BT-MCA0954] Drug Development and Evaluation Canalicular multispecific organic anion transporterThis gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non AUG translation initiation

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Description

Canalicular multispecific organic anion transporter 2 is a member of the MRP subfamily which is involved in multi-drug resistance

such as mitogenic activation

GO annotations related to this gene include cyclin-dependent protein serine/threonine kinase regulator activity

May be one regulator of transcriptional events during hemopoietic development

Mutations in STK11 have been associated with Peutz-Jeghers syndrome

Oct-3/4 Monoclonal Antibody, 50ul[BT-MCA0954] Drug Development and Evaluation Canalicular multispecific organic anion transporterThis gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non AUG translation initiation

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