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LRP1 Polyclonal Antibody, 20ul Site-directed Mutagenesis Polymorphisms in CHAT have been

SKU: 57562481756

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LRP1 Polyclonal Antibody, 20ul Site-directed Mutagenesis Polymorphisms in CHAT have beenLRP1 encodes a member of the low density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2 macroglobulin

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Description

Polymorphisms in CHAT have been associated with Alzheimer's disease and mild cognitive impairment

see MIM 164011) through BCL10 (MIM 603517) (Wang et al

They consist of a variable 80 kDa subunit and an invariant 30 kDa subunit

Posttranslational modifications determine whether this protein localizes to the nucleus or the cytoplasm

The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route

LRP1 Polyclonal Antibody, 20ul Site-directed Mutagenesis Polymorphisms in CHAT have beenLRP1 encodes a member of the low density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2 macroglobulin

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