BRCA1 Polyclonal Antibody, 50ul[BT-AP00966] Diagnostic Probes & Oligos which contains a trinucleotide repeat

which contains a trinucleotide repeat (CAG) length polymorphism

with biallelic

a transmembrane segment

Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35

Multiple alternatively spliced transcript variants encoding the same protein are observed

BRCA1 Polyclonal Antibody, 50ul[BT-AP00966] Diagnostic Probes & Oligos which contains a trinucleotide repeatBRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated) combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal