STAT2 Polyclonal Antibody, 100ul Cell fragmentation and collection The gene is located near

The gene is located near the Smith-Magenis syndrome region on chromosome 17

The encoded protein may also be involved in Parkinson disease and myotonic dystrophy

This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination

Disruption of this gene negatively impacts mitochondrial and cytosolic iron homeostasis

Intracellularly

STAT2 Polyclonal Antibody, 100ul Cell fragmentation and collection The gene is located nearThe protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this