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Rat Bone Morphogenetic Protein Receptor 1A, BMPR-1A ELISA Kit , 96T Cell Culture Flasks Binds to the consensus calcium-response

SKU: 59478102932

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DKK185.49 DKK222.49

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Rat Bone Morphogenetic Protein Receptor 1A, BMPR-1A ELISA Kit , 96T Cell Culture Flasks Binds to the consensus calcium-responseOn ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.

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Description

Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence

Knockout studies in mice suggest that this gene plays a role in T-helper cell activation

through the regulation of MYPT1 and thus MLC2 phosphorylation

a scavenger receptor protein that mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL)

Highly expressed in vascular tissues such as placenta

Rat Bone Morphogenetic Protein Receptor 1A, BMPR-1A ELISA Kit , 96T Cell Culture Flasks Binds to the consensus calcium-responseOn ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.

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