Phospho-B23 (T199) Polyclonal Antibody, 100ul Cellular Function Assays May play a role in

May play a role in cell cycle checkpoint control

This gene is expressed in different carcinomas

it does not constitute the catalytic RING subunit in the DCX DET1-COP1 complex that negatively regulates JUN

Diseases associated with RASGRF1 include bleeding disorder

an heteromultimeric enzyme that is present in intracellular vesicles and in the plasma membrane of specialized cells

Phospho-B23 (T199) Polyclonal Antibody, 100ul Cellular Function Assays May play a role inNPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified.