TCAL8 Polyclonal Antibody, 20ul Custom DNA Oligos Initiation of transcription by RNA

Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I

It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins

INTS2 (integrator complex subunit 2) is a subunit of the Integrator complex

enhances the generation of cytolytic T cells

Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS)

TCAL8 Polyclonal Antibody, 20ul Custom DNA Oligos Initiation of transcription by RNAThis gene encodes a member of the transcription elongation factor A (SII) like (TCEAL) gene family. Members of this family contain TFA domains and may function as nuclear phosphoproteins that modulate transcription in a promoter context dependent manner. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform.