RASL2 Polyclonal Antibody, 50ul Digital Burette Chromosomal translocations have been characterized

Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b

forms the DNA polymerase alpha complex

This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals

The activation is rapid and specific

in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini

RASL2 Polyclonal Antibody, 50ul Digital Burette Chromosomal translocations have been characterizedThis gene encodes a member of the GAP1 family of GTPase activating proteins that suppresses the Ras mitogen activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP bound state to the inactive GDP bound state and no longer activates downstream