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Rb (Acetyl-K873/K874) Polyclonal Antibody, 20ul Vortex Mixer Involved in neuronal differentiation

SKU: 62644229039

4.1
SEK97.20 SEK147.20

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Rb (Acetyl-K873/K874) Polyclonal Antibody, 20ul Vortex Mixer Involved in neuronal differentiationThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

Involved in neuronal differentiation

Several transcript variants encoding different isoforms have been found for this gene

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues

also named as CK1

Promotes endocytosis| possesses opsonic properties and influences the mineral phase of bone

Rb (Acetyl-K873/K874) Polyclonal Antibody, 20ul Vortex Mixer Involved in neuronal differentiationThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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