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Endo G-L1 Polyclonal Antibody, 50ul Purification The small GTPase Rac1 has

SKU: 63073237923

4.1
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Endo G-L1 Polyclonal Antibody, 50ul Purification The small GTPase Rac1 hasEXOG encodes an endo exonuclease with 5' 3' exonuclease activity. The encoded enzyme (endo exonuclease (5' 3'), endonuclease G like) catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18.

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Description

The small GTPase Rac1 has been shown to bind and regulate the activity of this protein

2 extracellular

The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors

and may have an important role as a potential gene therapy target

Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS)

Endo G-L1 Polyclonal Antibody, 50ul Purification The small GTPase Rac1 hasEXOG encodes an endo exonuclease with 5' 3' exonuclease activity. The encoded enzyme (endo exonuclease (5' 3'), endonuclease G like) catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18.

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