VRK3 Polyclonal Antibody, 50ul Cell Culture Plates FGF receptor substrates (FRS2 and

FGF receptor substrates (FRS2 and FRS3) are key adaptor proteins that mediate FGF-FGFR signalling in benign as well as malignant tissue

has been identified for this gene

This gene encodes the delta subunit of the translocon-associated protein complex which is involved in translocating proteins across the endoplasmic reticulum membrane

For example in human platelets a single band of 150kDa was detected

The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily

VRK3 Polyclonal Antibody, 50ul Cell Culture Plates FGF receptor substrates (FRS2 andVRK3 (vaccinia related kinase 3) encodes a member of the vaccinia related kinase (VRK) family of serine threonine protein kinases. In both human and mouse, VRK3 has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis. In vitro assays indicate the protein lacks phosphorylation activity. The protein, however, likely retains its substrate binding capability. VRK3 is widely