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LATS1/2(Phospho Thr1079/1041) Polyclonal Antibody, 20ul Centrifuges SERPINB7 (serpin family B member

SKU: 63680179133

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DKK97.20 DKK126.20

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LATS1/2(Phospho Thr1079/1041) Polyclonal Antibody, 20ul Centrifuges SERPINB7 (serpin family B memberThe protein encoded by this gene is a putative serine threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell cycle dependent manner, with late prophase phosphorylation remaining through metaphase. The N terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative

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Description

SERPINB7 (serpin family B member 7) encodes a member of a family of proteins which function as protease inhibitors

Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy

This gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea

and it is found in the mitochondrial intermembrane space in healthy cells

CYP2D6 can vary in copy number and individuals with the ultrarapid metabolizer phenotype can have 3 or more active copies of the gene

LATS1/2(Phospho Thr1079/1041) Polyclonal Antibody, 20ul Centrifuges SERPINB7 (serpin family B memberThe protein encoded by this gene is a putative serine threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell cycle dependent manner, with late prophase phosphorylation remaining through metaphase. The N terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative

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