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STEAP2 Polyclonal Antibody, 100ul Glassware Sets Defects in this gene may

SKU: 63980650982

4.3
PLN141.00 PLN183.00

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STEAP2 Polyclonal Antibody, 100ul Glassware Sets Defects in this gene maySTEAP2 is a member of the STEAP family and encodes a multi pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression.

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Description

Defects in this gene may be a cause of J-wave syndromes and sudden infant death syndrome (SIDS)

and 30-300 µl

Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK)

Inhibition of the encoded protein restores hemostasis in animal models of hemophilia

Naturally occurring read-through transcription exists between upstream ATP5J2 (ATP synthase| H+ transporting| mitochondrial Fo complex| subunit F2) and this gene

STEAP2 Polyclonal Antibody, 100ul Glassware Sets Defects in this gene maySTEAP2 is a member of the STEAP family and encodes a multi pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression.

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