Ku-70 (Acetyl Lys338) Rabbit Polyclonal Antibody, 100ul Protein Analysis In both human and mouse

In both human and mouse

It is an essential component of the transcription factor TFIIH

This region is duplicated elsewhere in the human genome

This protein has two distinct roles in spindle formation

The hnRNP proteins have distinct nucleic acid binding properties

Ku-70 (Acetyl Lys338) Rabbit Polyclonal Antibody, 100ul Protein Analysis In both human and mousedevelopmental stage: Expression does not increase during promyelocyte differentiation. disease: Individuals with systemic lupus erythematosus (SLE) and related disorders produce extremely large amounts of autoantibodies to p70 and p86. Existence of a major autoantigenic epitope or epitopes on the C terminal 190 amino acids of p70 containing the leucine repeat. The majority of autoantibodies to p70 in most sera from patients with SLE seem to be