NFKappaB-p65 (Acetyl Lys218) Polyclonal Antibody, 50ul Vessels Protein kinase C (PKC) is

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol

Mutations in this gene have been associated with hereditary hemochromatosis type III

which shows little similarity to any of the other known human DEAD box proteins

subcellular location:Lacks the PDZ domain

Down-regulated in immortalized fibroblasts isolated after a proliferative crisis accompanied with massive cell death

NFKappaB-p65 (Acetyl Lys218) Polyclonal Antibody, 50ul Vessels Protein kinase C (PKC) isNF kappa B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF kappa B moves to the nucleus and activates transcription of specific genes. NF kappa B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF kappa B is NFKB1 complexed with the product of this gene, RELA. Four