OTUD4 Polyclonal Antibody, 20ul Human Genome Knockout Libraries Caspase 2 may function in

Caspase 2 may function in stress-induced cell death pathways

Specific mutations in DYSF have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy

The protein encoded by this gene is a component of the F-type ATPase found in the mitochondrial matrix

and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma

The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B| subunit 1 activation that is required for cell activation and protection against apoptosis

OTUD4 Polyclonal Antibody, 20ul Human Genome Knockout Libraries Caspase 2 may function inAlternatively spliced transcript variants have been found for this gene. The smaller protein isoform encoded by the shorter transcript variant is found only in HIV 1 infected cells.