4E-BP1 Polyclonal Antibody, 50ul[BT-AP00035] Miscellaneous The M channel is formed

The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene

is associated with clathrin

Alternative splicing of TOP2B results in two transcript variants

An important paralog of this gene is CADM3

which may inhibit TGFB signaling

4E-BP1 Polyclonal Antibody, 50ul[BT-AP00035] Miscellaneous The M channel is formedEIF4EBP1 encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV