Rb Polyclonal Antibody, 20ul[BT-AP07692] Metabolic enzymes PAX1 is silenced by methylation

PAX1 is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene

G protein-coupled receptor 132 was reported to be a receptor for lysophosphatidylcholine action

possibly by restricting MDM2 from extending polyubiquitin chains on ubiquitinated p53/TP53

MYL3 encodes myosin light chain 3

such as C/EBP and LAP (liver activator protein)

Rb Polyclonal Antibody, 20ul[BT-AP07692] Metabolic enzymes PAX1 is silenced by methylationThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.