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Stat5a Polyclonal Antibody, 20ul[BT-AP08640] Multiplex Immunoassays The encoded preproprotein is secreted

SKU: 67039933585

4.3
SEK111.00 SEK148.00

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Stat5a Polyclonal Antibody, 20ul[BT-AP08640] Multiplex Immunoassays The encoded preproprotein is secretedThe protein encoded by STAT5A (signal transducer and activator of transcription 5A) is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands,

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Description

The encoded preproprotein is secreted by hepatocytes and proteolytically processed to generate heavy and light chains that form the mature heterodimer

CIDE-B is expressed mainly in liver and at lower levels in spleen

the expression and stability of the regulatory subunit fluctuates depending on the stage of the cell cycle and

Cleavage stimulation factor subunit 2 is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs

This gene product binds to and inactivates p38 and SAPK/JNK

Stat5a Polyclonal Antibody, 20ul[BT-AP08640] Multiplex Immunoassays The encoded preproprotein is secretedThe protein encoded by STAT5A (signal transducer and activator of transcription 5A) is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands,

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