MSK2(Phospho Thr568) Polyclonal Antibody, 100ul Stepper Inhibits SIRT1 in a CHEK2

Inhibits SIRT1 in a CHEK2 and PSEM3-dependent manner and inhibits the activity of CHEK2 in vitro (PubMed: 25361978)

This gene encodes a mitochondrially-localized protein with conserved B-cell lymphoma 2 homology motifs

At least eight components of the exocyst complex| including this protein| are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery

some of which are potentially toxic

Required for consolidation of synaptic plasticity as well as formation of long-term memory

MSK2(Phospho Thr568) Polyclonal Antibody, 100ul Stepper Inhibits SIRT1 in a CHEK2This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine threonine kinases. This kinase contains 2 non identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and ATF1. The encoded protein can also phosphorylate histone H3 to regulate certain inflammatory genes. Several transcript variants encoding different isoforms have been found for this gene.