WFS1 Polyclonal Antibody, 20ul Cell Screening and Imaging Melanoma inhibitory activity (cartilage-derived retinoic

Melanoma inhibitory activity (cartilage-derived retinoic acid-sensitive protein (CD-RAP)

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a member of the epidermal growth factor receptor family of receptor tyrosine kinases

The active site residues of carboxypeptidases A and B are conserved in this protein

Overexpression of the encoded protein may be associated with astrocytoma progression

WFS1 Polyclonal Antibody, 20ul Cell Screening and Imaging Melanoma inhibitory activity (cartilage-derived retinoicThis gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system.