FoxO3a(Phospho-Ser7) Rabbit Polyclonal Antibody, 20ul Centrifugal Filter an Arf-GAP domain

an Arf-GAP domain

also known as keratosis follicularis

These domains bind to carbohydrates in the presence of calcium| and may be involved in cell adhesion| immune response and apoptosis

and cellular activation and has been linked to Gray platelet syndrome

Binds PLXNA1 (By similarity)

FoxO3a(Phospho-Ser7) Rabbit Polyclonal Antibody, 20ul Centrifugal Filter an Arf-GAP domainThis gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.