SYT8 Polyclonal Antibody, 20ul Metabolic enzymes Three alternatively spliced variants encoding

Three alternatively spliced variants encoding different isoforms have been described for this gene

Gene Ontology (GO) annotations related to this gene include nucleic acid binding and transcription factor activity

It is found in mitochondria| peroxisomes| and the cytoplasm

Many recombinant proteins have been engineered to express the HA tag| which does not appear to interfere with the bioactivity or the biodistribution of the recombinant protein

Methylation of DNA is an important component of mammalian epigenetic gene regulation

SYT8 Polyclonal Antibody, 20ul Metabolic enzymes Three alternatively spliced variants encodingThis gene encodes a member of the synaptotagmin protein family. Synaptotagmins are membrane proteins that are important in neurotransmission and hormone secretion, both of which involve regulated exocytosis. Expression of the encoded protein in human pancreatic islets has been connected to activity of the promoter for the insulin gene, on the same chromosome several hundred kilobases away (PMID: 21336277 and 22928559). This association would link