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LRIG1 Polyclonal Antibody, 20ul Variant Libraries Temperature range: -80°C–121°C (does not

SKU: 6958547633

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LRIG1 Polyclonal Antibody, 20ul Variant Libraries Temperature range: -80°C–121°C (does notThe LRRs and the Ig domains are each sufficient for EGFR ERBB1 binding. This interaction is abolished only when these two domains are deleted.,Act as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.,induction: By EGF.,Contains 17 LRR (leucine rich) repeats.,Contains 3 Ig like C2 type (immunoglobulin like)

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Description

Temperature range: -80°C–121°C (does not deform after high-temperature sterilization and remains highly transparent)

The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase

Alternative splicing seems to be a common mechanism in this gene family

The mammalian protein is involved in tumor suppression pathways

There are 3 distinct domains of this factor: extracellular

LRIG1 Polyclonal Antibody, 20ul Variant Libraries Temperature range: -80°C–121°C (does notThe LRRs and the Ig domains are each sufficient for EGFR ERBB1 binding. This interaction is abolished only when these two domains are deleted.,Act as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.,induction: By EGF.,Contains 17 LRR (leucine rich) repeats.,Contains 3 Ig like C2 type (immunoglobulin like)

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