LAP2B Polyclonal Antibody, 20ul Custom DNA Oligos Protein phosphatase 2A holoenzymes are

Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A

Regulates signaling cascades probably through protein ubiquitination and/or sequestration

This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus

The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes

The product of this gene belongs to the Serine/Threonine protein kinase family| and to the Ca(2+)/calmodulin-dependent protein kinase subfamily

LAP2B Polyclonal Antibody, 20ul Custom DNA Oligos Protein phosphatase 2A holoenzymes arealternative products: Additional isoforms seem to exist,Has two structurally independent, non interacting domains: LEM like (also called LAP2 N or LEM D) and LEM (also called LAP2 C or LEM B). LEM like binds DNA while LEM interacts with BANF1.,May be involved in the structural organization of the nucleus and in the post mitotic nuclear assembly. Play an important role, together with LMNA, in the nuclear anchorage of RB1.,May help direct the assembly