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LTOR2 Polyclonal Antibody, 50ul DNA Libraries Synthesis This gene encodes the sacsin

SKU: 70247763098

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LTOR2 Polyclonal Antibody, 50ul DNA Libraries Synthesis This gene encodes the sacsinThe product of this gene is highly conserved with a mouse protein associated with the cytoplasmic face of late endosomes and lysosomes. The mouse protein interacts with MAPK scaffold protein 1, a component of the mitogen activated protein kinase pathway. In humans, a mutation in this gene has been associated with a primary immunodeficiency syndrome, and suggests a role for this protein in endosomal biogenesis. Multiple transcript variants encoding

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Description

This gene encodes the sacsin protein

This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane

The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex

This gene encodes a protein belonging to the sprouty family

it lacks peptidase activity

LTOR2 Polyclonal Antibody, 50ul DNA Libraries Synthesis This gene encodes the sacsinThe product of this gene is highly conserved with a mouse protein associated with the cytoplasmic face of late endosomes and lysosomes. The mouse protein interacts with MAPK scaffold protein 1, a component of the mitogen activated protein kinase pathway. In humans, a mutation in this gene has been associated with a primary immunodeficiency syndrome, and suggests a role for this protein in endosomal biogenesis. Multiple transcript variants encoding

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