Human Natural Killer Cell Receptor 2B4, CD244 ELISA Kit, 96T CellSafe™ This gene encodes a protein

This gene encodes a protein containing tetratricopeptide repeat and a U-box that functions as a ubiquitin ligase/cochaperone

using magnesium as a cofactor

Mutations in this gene are associated with hereditary hemorrhagic telangiectasia

Expressed in 22% of melanomas

Multiple alternatively spliced variants encoding the same protein have been identified

Human Natural Killer Cell Receptor 2B4, CD244 ELISA Kit, 96T CellSafe™ This gene encodes a proteinHeterophilic receptor of the signaling lymphocytic activation molecule (SLAM) family; its ligand is CD48. SLAM receptors triggered by homo or heterotypic cell cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins,