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cPLA2(Phospho Ser505) Polyclonal Antibody, 50ul Contamination Detection & Removal This gene encodes a member

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PLN162.00 PLN189.00

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cPLA2(Phospho Ser505) Polyclonal Antibody, 50ul Contamination Detection & Removal This gene encodes a memberThis gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids

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Description

This gene encodes a member of the HEXIM family of proteins

CENPB (MIM 117140)

Mutations and deletions in this gene are associated with benign hereditary chorea| choreoathetosis| congenital hypothyroidism| and neonatal respiratory distress| and may be associated with thyroid cancer

in particular the anaplastic lymphoma kinase gene on chromosome 2

The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2

cPLA2(Phospho Ser505) Polyclonal Antibody, 50ul Contamination Detection & Removal This gene encodes a memberThis gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids

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