APBB3 Rabbit Polyclonal Antibody, 50ul Syringe Filter The function of RIOK1 has

The function of RIOK1 has not been determined

Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy

and endocytic recycling of LDL receptors

The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells

Seems to be coupled to the G(i)/G(o)

APBB3 Rabbit Polyclonal Antibody, 50ul Syringe Filter The function of RIOK1 hasThe protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta amyloid precursor protein (APP) as well as to other APP like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene.