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IRP-1 Polyclonal Antibody, 50ul[BT-AP04640] Molecular Weight Markers |Contains 1 Rho-GAP domain

SKU: 72257339514

4.4
USD162.00 USD186.00

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IRP-1 Polyclonal Antibody, 50ul[BT-AP04640] Molecular Weight Markers |Contains 1 Rho-GAP domainThe protein encoded by ACO1 is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein binds to a 4Fe 4S cluster and functions as an aconitase. Aconitases are iron sulfur proteins that function to catalyze the conversion of citrate to isocitrate. When cellular iron levels are low, the protein binds to

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Description

|Contains 1 Rho-GAP domain

More variants may exist| but their full-length natures could not be determined

Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins

and no basal expression

Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression

IRP-1 Polyclonal Antibody, 50ul[BT-AP04640] Molecular Weight Markers |Contains 1 Rho-GAP domainThe protein encoded by ACO1 is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein binds to a 4Fe 4S cluster and functions as an aconitase. Aconitases are iron sulfur proteins that function to catalyze the conversion of citrate to isocitrate. When cellular iron levels are low, the protein binds to

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