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Phospho-AR (S213) Polyclonal Antibody, 20ul High Speed Micro-Centrifuges The shorter isoform has been

SKU: 72505203912

4.1
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Phospho-AR (S213) Polyclonal Antibody, 20ul High Speed Micro-Centrifuges The shorter isoform has beenThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. AR

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Description

The shorter isoform has been shown to display weaker transforming activity

Pseudogenes are present on chromosomes 5 and 22

Multiple alternatively spliced variants encoding different isoforms have been described

The GNL1 gene

The encoded protein may function in stress-induced cell death pathways

Phospho-AR (S213) Polyclonal Antibody, 20ul High Speed Micro-Centrifuges The shorter isoform has beenThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. AR

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