Mad 4 Polyclonal Antibody, 20ul Protein Analysis has been identified as a
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Mad 4 Polyclonal Antibody, 20ul Protein Analysis has been identified as aMXD4 is a member of the MAD gene family. The MAD genes encode basic helix loop helix leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating
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