TPH2(Phospho Ser19) Polyclonal Antibody, 20ul Cell Culture Dishes Interacts with the Axin complex

Interacts with the Axin complex

It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein

Pseudogenes of this gene are present on chromosomes 1| 3| 9| 12 and 20| and on the X chromosome

It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity

and the target SNAREs (t-SNARE) syntaxin and SNAP-25

TPH2(Phospho Ser19) Polyclonal Antibody, 20ul Cell Culture Dishes Interacts with the Axin complexThis gene encodes a member of the pterin dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.