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KV401 Rabbit Polyclonal Antibody, 50ul Enzymes & Activity Assays This locus represents a polymorphic

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KV401 Rabbit Polyclonal Antibody, 50ul Enzymes & Activity Assays This locus represents a polymorphic

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Description

This locus represents a polymorphic pseudogene| where some individuals contain an allele that can encode a full-length protein| while others have a non-functional allele containing a premature stop codon (reference SNP rs237520) that truncates the coding sequence

This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia| and expansion of CGG repeats in the 5' UTR has been associated with Jacobsen syndrome

Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth

one Ras-GAP domain and one WW domain

The encoded protein (mannan binding lectin serine peptidase 1) is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway

KV401 Rabbit Polyclonal Antibody, 50ul Enzymes & Activity Assays This locus represents a polymorphic

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