IKK Alpha/Beta Polyclonal Antibody, 50ul[BT-AP04421] Rotator The encoded protein is localized

The encoded protein is localized to the brush border membrane of the intestinal epithelium and mediates the uptake of di- and tripeptides from the lumen into the enterocytes

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as well as a heightened responsiveness of human bronchial epithelial cells (HBECs) to C5a upon exposure of these cells to cigarette smoke and other environmental irritants

tissue specificity:Highly expressed in testis and thymus

Mutations in this gene have been observed in individuals with amyotrophic lateral sclerosis 20

IKK Alpha/Beta Polyclonal Antibody, 50ul[BT-AP04421] Rotator The encoded protein is localizedCHUK encodes a member of the serine threonine protein kinase family. Inhibitor of nuclear factor kappa B kinase subunit alpha, a component of a cytokine activated protein complex that is an inhibitor of the essential transcription factor NF kappa B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.